Quantitative imaging of the clearance systems in the eye and the brain.

Quantitative Imaging in Medicine and Surgery, 2020; 10(1):1-14

Pile Of Books

Selected Publications

 

Journal of Magnetic Resonance Imaging (in press)

Role of structural, metabolic, and functional MRI in monitoring visual system impairment and recovery.

JR Sims, AM Chen, Z Sun, W Deng, NA Colwell, MK Colbert, J Zhu, A Sainulabdeen, MA Faiq, JW Bang, KC Chan.

Quantitative Imaging in Medicine and Surgery, 2020; 10(1):1-14

Quantitative imaging of the clearance systems in the eye and the brain.

W Deng, C Liu, C Parra, JR Sims, MA Faiq, A Sainulabdeen, H Song, KC Chan

Progress in Retinal and Eye Research, 2019; 72:100767

Cholinergic nervous system and glaucoma: From basic science to clinical applications.

MA Faiq, G Wollstein, JS Schuman, KC Chan.

Scientific Reports, 2019; 9: 14168

Widespread brain reorganization perturbs visuomotor coordination in early glaucoma.

V Trivedi, JW Bang, C Parra, MK Colbert, C O’Connell, A Arshad, MA Faiq, IP Conner, MS Redfern, G Wollstein, JS Schuman, R Cham, KC Chan.

Acta Biomaterialia 2019; 94: 219-231.

Intracameral injection of a chemically cross-linked hydrogel to study chronic neurodegeneration in glaucoma.

KC Chan, Y Yu, SH Ng, HK Mak, YW Yip, Y van der Merwe, T Ren, JS Yung, S Biswas, X Cao, Y Chau, CK Leung.

Frontiers in Neural Circuits, 2019; 13:35

Applications of manganese-enhanced magnetic resonance imaging in ophthalmology and visual neuroscience.

W Deng, MA Faiq, C Liu, V Adi, KC Chan.

Neural Regeneration Research, 2019; 14(3):446-449

In vivo imaging of structural, metabolic and functional brain changes in glaucoma.

A Kasi, MA Faiq, KC Chan.

Scientific Reports 2018; 8:4643.

Age-related changes in eye, brain and visuomotor behavior in the DBA/2J mouse model of chronic glaucoma.

XL Yang, Y van der Merwe, J Sim, C Parra, LC Ho, JS Schuman, G Wollstein, KL Lathrop, KC Chan.

Scientific Reports, 2017; 7:43124

Longitudinal assessments of normal and perilesional tissues in focal brain ischemia and partial optic nerve injury with manganese-enhanced MRI.

KC Chan, SS Liu, Y van der Merwe, IY Zhou, SJ Fan, VK Hung, SK Chung, WT Wu, KF So, EX Wu

Experimental Eye Research 2017; 160:85–95

Whole-globe biomechanics using high-field MRI.

AP Voorhees, LC Ho, NJ Jan, H Tran, Y van der Merwe, KC Chan*, IA Sigal* (*Co-corresponding authors)

Scientific Reports, 2016; 6:32080.

Non-invasive MRI assessments of tissue microstructures and macromolecules in the eye upon biomechanical or biochemical modulation.

LC Ho, IA Sigal, NJ Jan, XL Yang, Y van der Merwe, Y Yu, CK Leung, IP Conner, T Jin, EX Wu, SG Kim, G Wollstein, JS Schuman, KC Chan.

Scientific Reports, 2016; 6:31464.

Retinal structures and visual cortex activity are impaired prior to clinical vision loss in glaucoma.

MC Murphy, IP Conner, C Teng, JD Lawrence, Z Safiullah, B Wang, RA Bilonick, SG Kim, G Wollstein, JS Schuman, KC Chan.

NeuroImage, 2016:125:932-40

Top-down influence on the visual cortex of the blind during sensory substitution.

MC Murphy, AC Nau, C Fisher, SG Kim, JS Schuman, KC Chan.

Neural Regeneration Research, 2015; 10(11):1717-19.

Use of sensory substitution devices as a model system for investigating cross-modal neuroplasticity in humans.

AC Nau, MC Murphy, KC Chan.

Investigative Ophthalmology & Visual Science, 2015; 56(6): 3788-3800.

In vivo evaluation of white matter integrity and anterograde transport in visual system after excitotoxic retinal injury with multimodal MRI and OCT.

LC Ho, B Wang, IP Conner, Y van der Merwe, RA Bilonick, SG Kim, EX Wu, IA Sigal, G Wollstein, JS Schuman, KC Chan.

Investigative Ophthalmology & Visual Science, 2014;55(9):5662-72.

Magic angle-enhanced MRI of fibrous microstructures in sclera and cornea with and without intraocular pressure loading.

LC Ho, IA Sigal, NJ Jan, A Squires, Z Tse, EX Wu, SG Kim, JS Schuman, KC Chan.

Investigative Ophthalmology & Visual Science, 2014;55(6):3747-57.

In vivo assessment of aqueous humor dynamics upon chronic ocular hypertension and hypotensive drug treatment using gadolinium-enhanced MRI.

LC Ho, IP Conner, CW Do, SG Kim, EX Wu, G Wollstein, JS Schuman, KC Chan.


Supported in part by

  • National Institutes of Health (R01 EY028125) 

  • BrightFocus Foundation National Glaucoma Research Program (G2013077, G2016030, G2019103) 

  • Alcon Research Institute Young Investigator Grant

  • ARVO Foundation for Eye Research

  • Feldstein Medical Foundation Research Grant

  • Research to Prevent Blindness/Stavros Niarchos Foundation International Research Collaborators Award

     

©2020 by NeuroImaging and Visual Science Laboratory