NeuroImaging and Visual Science Laboratory
Departments of Ophthalmology and Radiology, NYU Grossman School of Medicine
Quantitative imaging of the clearance systems in the eye and the brain.
Quantitative Imaging in Medicine and Surgery, 2020; 10(1):1-14
The Neuroscientist (in press)
Visual plasticity in adulthood: Perspectives from Hebbian and homeostatic plasticity
JW Bang, G Hamilton-Fletcher, KC Chan
Biology, 2022; 11(3): 454
Advanced Diffusion MRI of the Visual System in Glaucoma: From Experimental Animal Models to Humans
M Mendoza, M Shotbolt, MA Faiq, C Parra, KC Chan
In vivo MRI evaluation of anterograde manganese transport along the visual pathway following whole eye transplantation
C Komatsu, Y van der Merwe, L He, A Kasi, JR Sims, MR Miller, IA Rosner, AA Su, JS Schuman, KM Washington, KC Chan
Neural Regeneration Research, 2022; 17(5):937-947
Glymphatic imaging and modulation in the optic nerve
A Kasi, C Liu, MA Faiq, KC Chan
Neurotherapeutics, 2021; 18: 1339–1359
Citicoline modulates glaucomatous neurodegeneration through intraocular pressure-independent control
Y van der Merwe, MC Murphy, JR Sims, MA Faiq, XL Yang, LC Ho, IP Conner, Y Yu, CK Leung, G Wollstein, JS Schuman, KC Chan
Frontiers in Medicine 2021; 8:681169
Oral scutellarin treatment ameliorates retinal thinning and visual deficits in experimental glaucoma
J Zhu, A Sainulabdeen, K Akers, V Adi, JR Sims, E Yarsky, Y Yan, Y Yu, H Ishikawa, CK Leung, G Wollstein, JS Schuman, W Wei, KC Chan
Investigative Ophthalmology & Visual Science, 2021; 62(10): 21
Diffusion tensor imaging of visual pathway abnormalities in five glaucoma animal models
MK Colbert, LC Ho, Y van der Merwe, XL Yang, GJ McLellan, SA Hurley, AS Field, H Yun, Y Du, JH Fingert, C Parra, MA Faiq, G Wollstein, JS Schuman, KC Chan.
Journal of Magnetic Resonance Imaging, 2021; 54:1706–1729
Role of structural, metabolic, and functional MRI in monitoring visual system impairment and recovery
JR Sims, AM Chen, Z Sun, W Deng, NA Colwell, MK Colbert, J Zhu, A Sainulabdeen, MA Faiq, JW Bang, KC Chan.
Scientific Reports, 2021; 11: 15513
In vivo MRI evaluation of early postnatal development in normal and impaired eyes
J Au, S Kancherla, M Hamade, M Mendoza, KC Chan
Quantitative Imaging in Medicine and Surgery, 2020; 10(1):1-14
Quantitative imaging of the clearance systems in the eye and the brain
W Deng, C Liu, C Parra, JR Sims, MA Faiq, A Sainulabdeen, H Song, KC Chan
Progress in Retinal and Eye Research, 2019; 72:100767
Cholinergic nervous system and glaucoma: From basic science to clinical applications
MA Faiq, G Wollstein, JS Schuman, KC Chan.
Scientific Reports, 2019; 9: 14168
Widespread brain reorganization perturbs visuomotor coordination in early glaucoma
V Trivedi, JW Bang, C Parra, MK Colbert, C O’Connell, A Arshad, MA Faiq, IP Conner, MS Redfern, G Wollstein, JS Schuman, R Cham, KC Chan.
Acta Biomaterialia 2019; 94: 219-231.
Intracameral injection of a chemically cross-linked hydrogel to study chronic neurodegeneration in glaucoma
KC Chan, Y Yu, SH Ng, HK Mak, YW Yip, Y van der Merwe, T Ren, JS Yung, S Biswas, X Cao, Y Chau, CK Leung.
Frontiers in Neural Circuits, 2019; 13:35
Applications of manganese-enhanced magnetic resonance imaging in ophthalmology and visual neuroscience
W Deng, MA Faiq, C Liu, V Adi, KC Chan.
Neural Regeneration Research, 2019; 14(3):446-449
In vivo imaging of structural, metabolic and functional brain changes in glaucoma
A Kasi, MA Faiq, KC Chan.
Scientific Reports 2018; 8:4643.
Age-related changes in eye, brain and visuomotor behavior in the DBA/2J mouse model of chronic glaucoma
XL Yang, Y van der Merwe, J Sim, C Parra, LC Ho, JS Schuman, G Wollstein, KL Lathrop, KC Chan.
Scientific Reports, 2017; 7:43124
Longitudinal assessments of normal and perilesional tissues in focal brain ischemia and partial optic nerve injury with manganese-enhanced MRI
KC Chan, SS Liu, Y van der Merwe, IY Zhou, SJ Fan, VK Hung, SK Chung, WT Wu, KF So, EX Wu
Experimental Eye Research 2017; 160:85–95
Whole-globe biomechanics using high-field MRI
AP Voorhees, LC Ho, NJ Jan, H Tran, Y van der Merwe, KC Chan*, IA Sigal* (*Co-corresponding authors)
Scientific Reports, 2016; 6:32080.
Non-invasive MRI assessments of tissue microstructures and macromolecules in the eye upon biomechanical or biochemical modulation
LC Ho, IA Sigal, NJ Jan, XL Yang, Y van der Merwe, Y Yu, CK Leung, IP Conner, T Jin, EX Wu, SG Kim, G Wollstein, JS Schuman, KC Chan.
Scientific Reports, 2016; 6:31464.
Retinal structures and visual cortex activity are impaired prior to clinical vision loss in glaucoma
MC Murphy, IP Conner, C Teng, JD Lawrence, Z Safiullah, B Wang, RA Bilonick, SG Kim, G Wollstein, JS Schuman, KC Chan.
NeuroImage, 2016:125:932-40
Top-down influence on the visual cortex of the blind during sensory substitution
MC Murphy, AC Nau, C Fisher, SG Kim, JS Schuman, KC Chan.
Neural Regeneration Research, 2015; 10(11):1717-19.
Use of sensory substitution devices as a model system for investigating cross-modal neuroplasticity in humans
AC Nau, MC Murphy, KC Chan.
Investigative Ophthalmology & Visual Science, 2015; 56(6): 3788-3800.
In vivo evaluation of white matter integrity and anterograde transport in visual system after excitotoxic retinal injury with multimodal MRI and OCT
LC Ho, B Wang, IP Conner, Y van der Merwe, RA Bilonick, SG Kim, EX Wu, IA Sigal, G Wollstein, JS Schuman, KC Chan.
Investigative Ophthalmology & Visual Science, 2014;55(9):5662-72.
Magic angle-enhanced MRI of fibrous microstructures in sclera and cornea with and without intraocular pressure loading
LC Ho, IA Sigal, NJ Jan, A Squires, Z Tse, EX Wu, SG Kim, JS Schuman, KC Chan.
Investigative Ophthalmology & Visual Science, 2014;55(6):3747-57.
In vivo assessment of aqueous humor dynamics upon chronic ocular hypertension and hypotensive drug treatment using gadolinium-enhanced MRI
LC Ho, IP Conner, CW Do, SG Kim, EX Wu, G Wollstein, JS Schuman, KC Chan.